Flexible
Contract Research > Hit Discovery
Through
our collaboration with De
Novo Pharmaceuticals,
Peakdale can offer unique chemotypes to explore
G-Protein Coupled Receptors
and other receptors/drug targets with pharmaceutical
relevance. By applying De Novo’s propriety
in silico design algorithms with ligand and site
information,
we can synthesis novel, lead-like molecules for
rapid hit discovery. Elaboration of these hits
improves
the SAR (Structural Activity Relationship) and
repeated design-make test cycles that rapidly delivers
promising
lead candidates for full lead optimisation either
by our customers or ourselves.
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